These 7 Natural Compounds Show 'Potential Use in COVID-19 Treatment': Journal 'Dove Medical Press'
Natural products "showed in vitro and in vivo antiviral activities against different respiratory viruses, including SARS-CoV-2," the study reads.
A new study published last week in Dove Medical Press assessed the effectiveness of natural products against SARS-CoV-2, the virus that causes COVID-19.
The study, titled “Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review,” carried out searches in PubMed, SciELO, and ScienceDirect databases for articles about “natural compounds recognized for their antiviral activity against SARS-CoV-2.”
The authors found that “[m]any natural products that have shown antiviral activity belong to the families of terpenoids, alkaloids, saponins and phenolics (including flavonoids and phenolic acids).”
These natural products, compounds or molecules extracted from plants, “showed in vitro and in vivo antiviral activities against different respiratory viruses, including SARS-CoV-2”:
hispidulin (a natural flavone, is found in various plant species such as Artemisia and Salvia)
quercetin (a flavonoid produced by many fruits and vegetables, including onions, apples, grapes, berries, broccoli, citrus fruits, cherries, and green tea)
rutin (a flavonoid glycoside found in various plants, like buckwheat, asparagus, and citrus fruits)
saikosaponin D (found in plants such as Bupleurum falcatum L., Bupleurum kunmingense, and Bupleurum kaoi)
glycyrrhizin (a plant glycoside extracted from licorice plant roots)
resveratrol (a polyphenolic compound found in red grapes, peanuts, red wine, and berries)
curcumin (found in the ginger-family plant Curcuma longa)
Among these, the authors emphasized in their conclusion that “[c]ompounds such as resveratrol, curcumin, and quercetin, widely known to have antiviral activity, have demonstrated in vitro antiviral activity against SARS-CoV-2.”
The Colombian authors’ affiliations include:
Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medellín, Colombia
Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia UdeA, Medellín, Colombia
Grupo Productos Naturales Marinos, Departamento de Farmacia, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia UdeA, Medellín, Colombia
Grupo de investigación, Promoción y prevención farmacéutica, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia UdeA, Medellín, Colombia
You can download the full study below:
